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Home » Science of Sleep: Dr. Michelle Olaithe (Transcript)

Science of Sleep: Dr. Michelle Olaithe (Transcript)

Here is the full transcript of Dr. Michelle Olaithe’s talk titled “Science of Sleep” at TEDxMandurah 2021 conference.

Listen to the audio version here:

TRANSCRIPT:

The World Record for Sleep Deprivation

In 1964, Randy Gardner, some college friends and a university professor, Professor William Dement, decided to go for the world record of days without sleep. After day two, Randy could barely hold his eyes open, and he couldn’t repeat simple tongue twisters. His friends were falling asleep leaned up against the wall. By day three, he was uncoordinated and moody.

By day five, he was hallucinating. He managed to make it to 11 days and 25 minutes before he was rushed to the local naval hospital, where he spent, for the first night, 14 hours asleep, and spent the majority of that time in deep and dreaming sleep – these are your restorative sleep states.

Moving on to other research, Williamson and Feyer show us that if you spend around 15 to 19 hours deprived of sleep, you will behave as if your blood alcohol level is 0.05. That’s drunk.

Your reaction times will be 50 percent slower, and your accuracy will be abysmal. If I got you drunk and I gave you your keys, would you drive home? At the end of a long shift at work, if I gave you your keys, would you drive home? Now, in one of these situations, you’re going to be arrested, and in the other situation, you’ll be thanked for your time and paid.

The Importance of Sleep for Health and Well-being

The answers to these questions tell us a lot about how we as a society value sleep, and as individuals, how we value sleep. We know from the research that if you don’t get around 7 to 9 hours on average of sleep per night as an adult, it’s going to impact your mood, your health, increase your accident rate, and it’s less likely that your marriage will work out. The relationship between sleep and mental health is intimately and bidirectionally intertwined.

Traditionally, we thought that if you had sleep symptoms, it was a symptom of your mental health problem. However, we now know that poor sleep wreaks absolute havoc on your neurotransmitters and your stress hormones, making it really hard for you to think straight and for you to maintain a good mood. The stats on sleep and health tell us exactly the same story.

If you have disturbed sleep, you’re more likely to have a cardiovascular event, get diabetes, get cancer. And if you’re an under-sleeper, that’s a person who sleeps for six hours or less, or an over-sleeper, that’s a person who sleeps for 10 hours or more, you’re at higher risk of all-cause mortality. We are not going to work ourselves to death; we’re going to wake ourselves to death.

The Healing Power of Sleep

However, each night all of you hold a key, a magical pill to help you rewire and heal your brain. Even Randy Gardner held that key, because when Randy went to sleep and he spent the majority of his time in deep and dreaming sleep, he was healing. During deep sleep, you open up your brain’s dedicated waste clearance system – this is your glymphatic system.

And this system, made up of all these beautiful little glial cells that kind of look like stars, pulse with your cardiovascular system at night time. The point to this system is to wash the metabolites out of your brain and bring fresh supplies in so that you can work well the next day. We know that in people where they have disturbed sleep or their glymphatic system can’t work well because of cardiovascular problems or older age, we don’t wash these metabolites out of our brains so well.

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They build up in our brain, and it puts us at a seven to 27 percent higher risk of cognitive dysfunction and of dementia in later life. But I say to you that you are waking yourself to death but you can sleep yourself well. The other sleep state that Randy spent the majority of his time in was dreaming sleep.

During the day, you process hundreds of thousands of events that prime synapses – those are the connections between your neurons or your nerve cells – that need further processing. When you go into dreaming sleep, your brain processes those primed synapses further, creating proteins and laying down long-term memories. The other thing that happens is that you prune away the synapses that you don’t use very often, and that makes your brain more effective and more efficient.

Three Locks on Your Sleep and Three Keys to Unlock Them

So what I want to talk to you about today are three locks on your sleep and three keys for you to unlock that. And you can start these changes tonight. Lock number one: dirty bedtime habits.

In the 1890s, there was a Russian behavioral scientist called Pavlov, and he took some dogs and some bells and some meat. And every time he’d ring the bell, he would present the dog with some meat, and that would make the dog salivate. With enough pairings of the stimulus, which is the bell, with the reward, the meat, he could make the dog salivate just by presenting the bell.

You are an animal, and so you can train yourself behaviorally in this way as well. With enough presentations – clean presentations – of the bed with feeling sleepy, eventually, the bed is enough to make you feel sleepy. But they need to be clean presentations.

So that brings you to key number one: Clean your routine. If you have a clean routine, your body learns. And your body learns to give you melatonin at night to make you go to sleep at the same time, and cortisol in the morning to make you wake up and feel refreshed.

The Importance of a Consistent Sleep Routine

Now, when we’re talking about the amount of sleep you get, we also want quality of sleep.