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Home » Transcript: President Trump’s Remarks on Regeneron Deal – April 23, 2026

Transcript: President Trump’s Remarks on Regeneron Deal – April 23, 2026

Editor’s Notes: President Donald Trump hosted a White House event on April 23, 2026, to announce a landmark deal with Regeneron Pharmaceuticals aimed at lowering prescription drug prices for Medicaid. As part of the administration’s “Most Favored Nation” initiative, the agreement ensures that American patients pay prices in line with the lowest rates offered in other developed countries. The announcement highlighted significant price reductions for medications like Praluent and the provision of a new gene therapy for congenital hearing loss at no cost to eligible individuals. Joined by Health and Human Services Secretary Robert F. Kennedy Jr., the President characterized the deal as a transformative step in his broader mission to secure healthcare affordability.

TRANSCRIPT:

Regeneron Agrees to Most Favored Nation Pricing

TRUMP: Well, thank you very much. And today I’m thrilled to announce that one of the most respected pharmaceutical companies anywhere in the world, frankly, I know it very well, is Regeneron. And it’s agreed to offer their prescription medications at heavily discounted, most favored nation prices. The numbers will come down at levels that nobody’s ever seen before.

The whole most favored nation thing that we’ve been able to do with Bobby and Oz and everybody behind me, Marty, has been incredible. It’s the biggest price reduction in drugs in history. By itself, we should win the midterms, but it doesn’t work that way, unfortunately. It doesn’t work that way. People forget too quickly. But it’s the biggest cut in drug prices in the history of our country by many percentage points.

17 Pharmaceutical Companies Now on Board

With this announcement, 17 of the world’s largest pharmaceutical companies, representing 80% of the branded drug market, have now agreed to sell their drugs to American patients at the lowest prices anywhere in the world. They have the lowest prices in the world. This will result in the largest drop in prescription drug prices in the history of the United States of America.

I mean, it should be front page news, but it won’t be. It’ll be back on page 19, but the people get it. That’s why we’re in the Oval Office, I guess.

Acknowledgements

I want to thank Regeneron CEO, a friend of mine for a long time. Good, good guy. Great guy. CEO Len Schleifer and Chief Scientific Officer George Yankopoulos, who are two fantastic people in the medical world. Very respected. We’re also joined by Secretary Robert F. Kennedy Jr. Bobby, thank you. Secretary Howard Lepnick, Administrator of the Centers for Medicare and Medicaid Services. Dr. Memonize is doing a fantastic job. They all are. FDA Commissioner Martin McCary and Chief Counselor of Health and Human Services. Chris Plump. Thanks, Chris. Great job. You’re doing great, Chris, wherever you may be.

Americans Have Paid the Highest Drug Prices in the World

For decades, Americans have been forced to pay the highest prices in the world for prescription drugs by far. Prices that were many, many times what the rest of the world was paying because we had a president that didn’t know what they were doing or they weren’t able to get other countries to agree to it. I was able to do that because I used tariffs. I said, if you don’t agree to it, we’re going to put tariffs in your country. And they said that we would be honored to do it, sir. After telling everybody now, including me, but they agreed to do it.

U.S. Consumers Bearing a Disproportionate Share of Drug Company Profits

The United States is just 4% of the world’s population and consumes only 13% of all prescription drugs. Yet pharmaceutical companies have been making 75% of their profits from American customers. So think of it — with 4% of the population and doing only 13% of all prescription drugs, the companies make 75%. I don’t know. Maybe hopefully they continue to — actually it’s not as bad for them as it sounds. In fact, many of their stocks are up because actually when the price goes up on the one end, they make up for the price coming down in the United States. So it really worked out pretty good.

Executive Order to Slash Prescription Drug Prices

To address this chronic unfairness, I signed an executive order instructing my administration to do everything in our power to slash prescription drug prices for Americans while getting other countries to pay more, in many cases, much more. But their other prices doubled and sometimes they tripled and ours would go down by 60, 70, 80% even more.

Regeneron’s Most Favored Nation Commitment and Drug Price Reductions

TRUMP: Today we’re building on our unprecedented success with Regeneron committing to offer all new drugs moving forward at most favored nation’s prices. They’ll make their current drugs available to Medicaid and MFN. It’s most favored nation. Additionally, they’ll also offer their current drug Praluent, which is the lower cholesterol and fight heart disease to all consumers at dramatically lower cost. It’ll come down from $537 to $225 and be available at trumprx.gov.

I didn’t put the name. Bobby did and Oz did. It’s true, actually. Remember I came in, I said, “What’s this? It’ll be better. It’ll sell better. Would you help us?” So, I now have my name on medication. But it’s doing great. I hear it’s setting records, actually. I was watching the other day and Mark Cuban of all people said, “It’s amazing what Trump has done with this.” I can’t believe when I heard him say that I was sort of in a state of shock. But others have said it too. This whole thing has turned out to be hot. So that’s trumprx.gov.

Regeneron’s $27 Billion Investment and FDA Approval of Otarmone

The company will also invest $27 billion to build up research and development at pharmaceutical manufacturing here in America, which is a big thank you very much.

Today, I’m also announcing that the FDA has just approved a new drug from Regeneron called Otarmone, a gene therapy curing a rare disease that causes deafness. People are totally deaf, and it’s amazing.