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Home » Transcript: Stanford CS153 Frontier Systems w/ Jensen Huang on the Compute Behind Intelligence

Transcript: Stanford CS153 Frontier Systems w/ Jensen Huang on the Compute Behind Intelligence

Editor’s Notes: In this captivating entry of Stanford Online’s Frontier Systems series, NVIDIA CEO Jensen Huang dives deep into the seismic shift reshaping the world of computer science. Speaking directly to an audience of students and innovators, Huang unpacks how the age of general-purpose computing is giving way to a new era of extreme “co-design,” where hardware and software are harmoniously built together to unlock millions-fold jumps in performance. He offers a masterclass in strategic thinking, mapping out the evolution from generative AI to advanced agentic systems while confronting real-world bottlenecks like energy and global compute scarcity. Ultimately, the interview stands as a powerful, first-principles look into the future of technology, driven by one of the industry’s most visionary leaders. (April 30, 2026) 

Welcome and Introduction

INTERVIEWER: I would like to welcome back Jensen Huang. We have been now in a — locked in a global race way faster than NASCAR racing. And it’s partly your fault. Jensen’s been the preacher that’s given us all the power we need, all the energy and some more, to have what I think has been the craziest 12 months of my life, certainly for many of you. And we’re just getting started.

The energy with which you approach every single thing you do, including the class last year, and then every time I’ve had the chance to hang out with you, you’ve given so much time to the students, to the founders. Thank you. Should we jump right in?

JENSEN HUANG: Yeah, let’s go.

INTERVIEWER: All right. We’re going to rapid fire. What is co-design and why is it so important?

JENSEN HUANG: I’ll answer that in a second.

INTERVIEWER: Yes, please.

The Reinvention of Computing

JENSEN HUANG: This is a great time to be in computer science. And obviously the reason is because computing is being reinvented for the first time as dramatically as it is — for the first time really in about 60+ years. The computer that we know of, that you all use, and our computing model, our mental model of a computer, the architecture of a computer, how you write the program, run the program, how you think about even taking computers to market, what it’s used for — for 64 years it has been largely the same since the IBM System/360. In fact, my first architecture book for learning about computer architecture was the System/360’s manual.

A lot has changed as we went from PCs to internet and mobile and cloud and all those things. But the fact of the matter is the computing model, the fundamental part of computer science, has largely remained the same until now. For the first time, the way you write the software, how you process the neural network versus the software, and what the applications can do has now dramatically changed. Everything is fundamentally different.

At the highest level, one simple way to think about it is: computing as we knew it before was largely prerecorded. It’s content that we prerecorded — images, videos, software that we largely prerecorded. But now everything is generated. And the nice thing about generating everything in real time is that it could be contextually consistent, contextually relevant to what it is that you’re dealing with. And of course, it can respond to your intention, not just explicitly to the things that you instruct. And so the computer is fundamentally different in that way.

Now the question is, what does that mean at every single layer of the stack? From how software is now developed, the methodology of it, how you organize your company to be able to develop software of today — completely changed. And so the methodology, the tools we use, the approach that we think about software coding — completely changed. How we run the software, neural network versus compiled binaries — very, very different. And so what does that mean to the computer system, the network, the storage? What does that mean to the software stack and the cloud services that sit on top of that? And of course, everything about the applications — what did it open up?

The Age of Agentic AI

Somebody just came and said, this piece of software we just opened up called Alpamayo. And I’ve been working on self-driving cars now for about 13 years. And the days of robo taxis are going to be literally everywhere. Everything that moves will be robotic. And that’s an example of an application that we wouldn’t consider doing until deep learning and artificial intelligence came along. That was such a big unlock that I said, hey, aha, this — all of these problems that we wanted to solve in the past that we needed computer vision for — are now fundamentally unlocked.

And so it’s how you think about every single stage of that. What is a software engineer? How do you organize the company? What is a computer for the age of AI? How do you architect that — all the way to what you can use it for and therefore where you would deploy it. All of that has fundamentally changed.

For me, the journey really started about 15 years ago. And I had the benefit of seeing some early works in the area. And as all Stanford students do, you break the problem down, you reason about it from first principles, and you come to the conclusion: literally everything has changed.

And so here you are, computer science students. This is really the first generation of AI becoming useful. A couple years ago, we were in the generative part of AI. And as you guys know, generative AI not only made it cool for us to do image generation and text summarization and translation and whatnot, but generative AI also enabled us to think.

When I saw generative AI, what other people saw was that it was able to generate images, and I surely appreciated that as well. But the fact that you can generate thoughts — in the form of images, but you can generate thoughts — you can also reason with it.