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Home » Diary Of A CEO: w/ Fatty Liver Expert Dr David Unwin (Transcript)

Diary Of A CEO: w/ Fatty Liver Expert Dr David Unwin (Transcript)

Read the full transcript of insulin expert Dr. David Unwin’s interview on The Diary Of A CEO Podcast, May 18, 2026.

Editor’s Notes: In this eye-opening episode of The Diary Of A CEO, host Steven Bartlett sits down with insulin expert Dr. David Unwin to uncover the silent epidemic sweeping across the developed world. Dr. Unwin breaks down how a staggering one-third of the population is living with fatty liver disease, an overlooked condition driven by hidden sugars and modern dietary habits. The conversation explores the direct link between a fatty liver and the collapse of insulin production, which leads to type 2 diabetes and hidden damage you might not even feel. Packed with practical advice, the episode introduces simple diagnostic metrics, the truth about the glycemic load, and powerful lifestyle interventions like low-carb diets that can reverse these conditions before it’s too late.

The Metabolic Health Crisis

STEVEN BARTLETT: Dr. David Unwin, you were named in 2018 among the top 10 most influential doctors in the United Kingdom. You’ve got an incredible list of accomplishments and you’re held in the highest regard, maybe of all the doctors I’ve ever had the chance to speak to, by many people that I’ve spoken to. We were talking before we started recording about what’s on your mind and what’s been bothering you. And so the floor is yours. What is front of mind for you, Dr. David?

DR. DAVID UNWIN: What’s front of mind for me is the idea that each of us has a number of different health futures. So in your future, I don’t know, there could be cancer, there could be multiple sclerosis, there could be many futures. What I’m interested in is how do I get you to pick a lifestyle that will get you the future you want? And I think that’s very difficult in the world now to know what is the best lifestyle, because you’re given so much conflicting advice.

The particular focus for me in terms of picking health futures is around young people, because they’ve got the longest time to make a difference. And it’s getting harder and harder and harder to make good health choices in your lifestyle. It’s really hard. I’d say it’s a pandemic of poor metabolic health. Yesterday in clinic, I saw two people under the age of 25 who had poorly controlled diabetes, and one of them was too heavy for me actually to weigh. And this situation is completely new. So when I was a young doctor and just starting off in practice, that was in 1986.

STEVEN BARTLETT: Wow.

DR. DAVID UNWIN: A long time ago, just north of Liverpool in the practice, I’m still there now. Obesity was rare and we didn’t have a single case of type 2 diabetes in anybody under 55. Not a single case. It was quite unknown. And in fact, type 2 diabetes had a different name. We’ve had to change the name because of the epidemic. It used to be called maturity onset diabetes. That meant old people, right? Now we call it type 2 diabetes because we have to include so many young people.

It’s really, really serious because people are losing their life expectancy. And I’m witnessing this. We’re all sleepwalking into a metabolic disaster and the people paying the greatest price, in my opinion, are young people. And it’s a scandal, and I’m hopping mad, really. I think we’ve started to normalize the dad bod, the big tummy, and haha, without realizing that maybe that isn’t how you’re supposed to be. So that’s what’s on my mind. Young people and their future, and they don’t even know.

The Opportunity to Change Your Health Future

STEVEN BARTLETT: You say young people there.

DR. DAVID UNWIN: Yeah.

STEVEN BARTLETT: Because they’ve got the biggest opportunity to change the trajectory of their health future.

DR. DAVID UNWIN: Yes.

STEVEN BARTLETT: But for the audiences listening that might be in their 50s now, is this advice also applicable?

DR. DAVID UNWIN: Absolutely. So we know from government figures, UK government figures, that for every year that you have poorly controlled type 2 diabetes, you’re losing 100 days of life. That’s about a third of a year, isn’t it? So whatever age you are, if you have poorly controlled diabetes, you’re losing life expectancy. And maybe a third of all the people in the world with type 2 diabetes don’t even know they have it because they haven’t taken a test, so they don’t know. What do you think kills people with type 2 diabetes?

STEVEN BARTLETT: Is it some cardiovascular issue?

DR. DAVID UNWIN: Yeah, well done. You’ve not been to medical school. You don’t know that. Most doctors, that’s what they’d say, because we know that a high blood sugar over time damages your arteries. So it’s a cumulative thing over time. But what you may not know is that actually a rising cause of mortality for people with diabetes is cancer.

STEVEN BARTLETT: Oh really?

DR. DAVID UNWIN: Yeah. So 8 forms of cancer are strongly associated with diabetes.

Understanding Diabetes: Type 1 vs. Type 2

STEVEN BARTLETT: I want to just define that term diabetes because I think I went through a lot of my life assuming that diabetes was a disease that some people are born with. And because I didn’t have it, I thought I don’t need to worry about that.

DR. DAVID UNWIN: That’s really important. So first of all, there’s type 1 diabetes and type 2. But before I can explain about diabetes, I need to explain about insulin. This is absolutely key to our whole discussion. So I’ve already said that a high blood sugar damages your arteries. And in fact, there’s work to show that a very high blood sugar damages the non-stick lining of your arteries within 6 hours. Really quick. It’s called the glycocalyx, the non-stick lining. And damage is occurring very quickly.

STEVEN BARTLETT: I’m going to ask you a really stupid question.

DR.