Skip to content
Home » Transcript: Trump Makes Drug Price Announcement Alongside AstraZeneca CEO

Transcript: Trump Makes Drug Price Announcement Alongside AstraZeneca CEO

Read the full transcript of President Trump and AstraZeneca CEO Pascal Soriot – press briefing making an announcement on most favored nation status drug pricing, Friday, October 10, 2025.

Trump Announces Historic Drug Price Reduction Agreement

PRESIDENT TRUMP: We have a lot of big announcements, sort of all big announcements, actually. It’s wonderful to be in the Oval Office. I think you probably like it the best. You like it the best for press conferences, that’s what I do. But today I’m excited to announce another historic achievement in our quest to lower drug prices for all Americans. You know, prices have come way down. We’ve gotten prices way down for groceries, for oil especially. Today we broke $60 a barrel. We think the oil is going to be under $2 a gallon very soon. That’s about 70% lower than what it was. That’s a year ago. So that’s a big thing. And when the oil comes down, everything comes down. It’s pretty beautiful to watch.

AstraZeneca Commits to Most Favored Nation Pricing

AstraZeneca, the largest pharmaceutical manufacturer in the United Kingdom, is committing to offer Americans major discounts on their vast catalog of prescription drugs. One of the great companies, by the way. And a Most Favored Nations pricing clause. So Most Favored Nation is you’re going to pay whatever the lowest price anywhere in the world is. That’s what you’re going to be paying. And I had it going very well in my first term, but we were interrupted by a rigged election. So I was unable to carry it forward. We started it. But this was something I, one of the reasons I wanted to run again was we had to have Favored Nations, where the world is not going to be paying just a fraction, just a tiny fraction of what we were paying.

I want to thank CEO Pascal Soriot, a very highly respected, one of the most respected men in business, and certainly in the industry, for joining us today, as well as Secretary Howard Lutnick, Secretary Robert F. Kennedy, Jr., CMS Administrator Mehmet Oz, FDA Commissioner Marty Makary, and Virginia Governor, a man who’s done an incredible job. And good luck with the upcoming election. I know you’re working very hard. I watch you. He’s out there working. He wants to see that young woman win. And the Attorney General, who I endorsed, et cetera, et cetera, Glenn Youngkin. Thank you very much, Glenn. Thank you for being here.

Historic Savings for American Taxpayers

For many years, Americans have paid the highest prices anywhere in the world for prescription drugs by far, by far. Many times the amount that other countries are paying is ridiculous. Upon taking office, I signed an executive order to make sure that Americans pay no more for prescription medications than the lowest price for the same drug in other locations in developing nations. Today, AstraZeneca is committing to offer all of their prescription medications to Medicaid at most favored nations prices. In other words, the lowest price anywhere in the world, that’s what we get, a move that will save American taxpayers hundreds of millions of dollars each year.

And I tell the story, Glenn, that in my first term, I had the honor of being the first president in 28 years to lower drug prices during the course of the year. And we actually did. And I was so proud of myself. We called a news conference. I announced it. It was one-eighth of 1 percent. One-eighth of 1 percent. Now drug prices are going to be going down 100 percent, 400 percent, 600 percent, a thousand percent in some cases. But for one-eighth of a cent, Bobby, think of that. I was so proud because for 28 years, nobody had done it. And now it’s, I think back to that, I said I shouldn’t have had that news conference. But it’s just true. I was the only one that did it, but it was not very much. And now we’re going to get, in some cases, a thousand percent reduction.

This is going to have a huge impact on everything from Social Security to Medicare to Medicaid. Anything where they’re buying any prescription drugs, it’s going to have an incredible impact. It’s going to lower itself greatly.

TrumpRX.gov Portal for Discounted Medications

AstraZeneca will also list many of their most popular drugs online at trumprx.gov. Trump R-X. I don’t know why they put the name Trump. I did not tell him to do it, but I’m honored to let him do it. It’s true, actually. That heavily reduced most favored nations’ costs. Americans can expect discounts. And as I said, it could be, in many cases, way over 100 percent. And as an example, one particular drug that’s hot, very hot, 654 percent on inhalers. COPD and asthma, as well as certain diabetics’ medications, they’re going to be averaging about 654 percent reduction in price. Do you believe that one? The Democrats will say, well, you should have gotten more. It’s crazy.

In addition, all medications AstraZeneca introduces to the American market going forward will also be sold at these heavily discounted rates. Furthermore, AstraZeneca will invest $50 billion in the United States over the next five years for research and development of new drugs and to onshore manufacturing facilities across the country, like the new plant that broke ground yesterday in Charlottesville, Virginia, where the governor attended. They had a tremendous group of people attending. It’s going to have 3,600 jobs just to begin with. And that’s going to be a fantastic plant. I saw a picture. It’s going to be the best, right? It can’t get any better.

This is a tremendous victory for Virginia and for American patients and for everything, for the country. It’s an amazing company to have coming over to the United States in such a big way. That’s going to be a big part of the company. Presidents have promised for years to lower the cost of healthcare, but my administration is actually the first to do it and do it substantially.