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Home » Transcript of Annie Jacobsen Interview: Biological Warfare on Shawn Ryan Show #323

Transcript of Annie Jacobsen Interview: Biological Warfare on Shawn Ryan Show #323

Episode Notes: In this episode of the Shawn Ryan Show, host Shawn Ryan welcomes back investigative journalist and New York Times best-selling author Annie Jacobsen. Building on her extensive work examining classified government programs and high-stakes national security threats, Jacobsen discusses the chilling realities outlined in her latest book, Biological Warfare: A Scenario. Together, they explore the severe dangers of airborne pathogens, the rising number of high-security biolabs worldwide, and whether the public is adequately prepared for a catastrophic biological event. (July 20, 2026)

Following is the full transcript of investigative journalist Annie Jacobsen‘s interview on SRS #323:

Introduction: The Reach of Podcasts

ANNIE JACOBSEN: I just love doing podcasts so much. It just gives somebody like me an opportunity to have a conversation. I mean, in the old days, you had to go on like a news program and talk for 4 minutes in between a commercial break.

SHAWN RYAN: They gave you 4 minutes, right? That’s generous.

ANNIE JACOBSEN: Yeah, yeah. Podcasts have reach. Okay. Good story. Shawn Ryan story. I’m in about podcasts having reach. I’m an avid skier. I’m in the Italian Alps in February, a few months ago. Okay, skiing. Little hut, like a hotel that you ski in, ski out. Couldn’t be more in the middle of nowhere in the Dolomite Mountains. There with the whole family. Go to settle the bill with the night manager at the end of the thing, and he says to me, “I have to say, I really enjoyed seeing you on the Shawn Ryan Show podcast.” In the Italian Alps. As God is my witness, and my husband who was standing there, right? And I said, “You’re kidding.” And he said no. And he said, “I’m a fan of the show and now I read your books.”

SHAWN RYAN: That’s awesome. That’s awesome.

ANNIE JACOBSEN: In the middle of the Italian Dolomite Mountains.

SHAWN RYAN: I’ll bet it’s beautiful up there.

ANNIE JACOBSEN: It’s gorgeous. But that’s reach for you. And it’s incredible to think about how much we are alike instead of— I mean, what really would you think the night manager at a small hotel in the mountains in Italy would necessarily have in common with you or I? And then you have that desire to communicate, desire for information, listening to a good podcast. So congratulations to you.

SHAWN RYAN: I appreciate that. Well, it’s good to have you back, Annie.

ANNIE JACOBSEN: Thank you. It’s great to be here.

SHAWN RYAN: Awesome to have you back. I love talking to you.

ANNIE JACOBSEN: Oh, I love talking to you.

Annie Jacobsen: Background and New Book

SHAWN RYAN: So let me give you an introduction here for anybody that missed the first episode. Annie Jacobsen, you’re a Pulitzer Prize finalist, investigative journalist, and New York Times bestselling author who spent your career uncovering some of the most secretive aspects of the U.S. government. You’ve written bestselling books including Area 51, Operation Paperclip, Flip the Pentagon’s Brain, Surprise Kill, Vanish, Nuclear War: A Scenario, and your newest release, Biological Warfare: A Scenario.

Everyone loved your last appearance on the show, so we’d love to have you back. And I have to say, Annie, I think your timelines are a little reversed here with the previous book Nuclear War and the new one Biological Warfare. But do you think about all this stuff going on? I mean, in Iran, the nuclear— I mean, I don’t think anything is going to happen.

ANNIE JACOBSEN: You mean, is the war in Iran ratcheting up the threat of nuclear war per se? I mean, it’s such a rabbit hole of a topic, that war. I don’t— because Iran doesn’t have a nuclear weapon and because the alleged premise of that war is to keep Iran from having a nuclear weapon. It exists in a little bit of a different lane than I am really interested in reporting on, which is what if a nuclear war happens? Because Iran has almost had a bomb for a very long time. So it does seem to me like an easy— I don’t want to use the word excuse, but I’m going to use the word excuse.

Biological Threats: Ticks, Pathogens, and the Alpha-Gal Concern

SHAWN RYAN: Yeah. Well, are you aware of the tick thing?

ANNIE JACOBSEN: Which tick thing?

SHAWN RYAN: Yeah, which tick thing? The meat, the alpha-gal. I mean, we’ve got people trying to force us to eat fake meat, artificial meat. Buying up all our farmland, then genetically altering insects, ticks. Now we have this alpha-gal disaster going on right now. I don’t know how many people have it, but what do you think of that?

ANNIE JACOBSEN: I think that anything talking about bio is like circling around what could eventually be the drain, unless something isn’t done. So in a bizarre way, bringing from where I sit — who just loves information, loves sharing information, loves having conversations about it — not right, not wrong, uncertainty being a huge principle — I think whether it’s the Legionnaires’ disease that just broke out in New York City right now, or the ticks you’re talking about—

SHAWN RYAN: What is that one? I don’t even— I haven’t even heard of that.

ANNIE JACOBSEN: It just happened yesterday.

SHAWN RYAN: Legionnaires’ disease? What is that?

ANNIE JACOBSEN: Like a small— you know, these are all pathogens that suddenly make their way into a small population, that is called an outbreak. And then the real question is, is it going to become an epidemic? Local. And then the real question is, is it going to become a pandemic?

So I think that any of these subjects that bring it to people’s attention— there’s an Ebola epidemic going on right now in Africa. There was a hantavirus scare on that cruise ship in May. These things surface, people talk about them, they learn a little bit.

To my eye, it’s just so much more helpful to kind of learn basics about bio and what a genetically modified pathogen is, than to either be terrified by it or politicize it, because everybody is going to lose if there’s a biological incident.

And interestingly, because of course I write about war and weapons, biological war is one of the only threats in the Defense Department world of nomenclature and monographs and protocols that doesn’t have to be an attack.